Most serums are one phase — water-based or oil-based. The Medicube Hyaluronic Multi Peptide PDRN Serum is a two-phase formula: an oil layer sitting above a serum layer, visible in the bottle. Shake before use to combine them. This mechanic isn't aesthetic — the oil layer (Neopentyl Glycol Dicaprate) seals the moisture delivered by the serum layer, extending hydration by preventing transepidermal water loss once applied. Underneath the oil layer, the serum delivers 13 types of peptides, Salmon DNA PDRN, alpha-arbutin and niacinamide. Fragrance-free. Hypoallergenic tested. 30ml.

• 13 Peptides — Every Major Mechanism Covered — Acetyl Hexapeptide-8 (Argireline: relaxes expression muscle contractions to reduce dynamic wrinkles); Copper Tripeptide-1 (GHK-Cu: supports collagen, elastin and GAG synthesis, wound healing); Palmitoyl Pentapeptide-4 + Palmitoyl Tripeptide-1 (Matrixyl 3000: the most clinically studied collagen-stimulating peptide pair); Palmitoyl Tetrapeptide-7 (Matrixyl Synthe'6 component: anti-inflammatory + collagen); Palmitoyl Hexapeptide-12 (plumping); Oligopeptide-1 (EGF analogue: stimulates epidermal growth factor receptors for cell renewal); Nonapeptide-1 (tyrosinase inhibitor: brightening); Dipeptide-2 (lymphatic drainage, de-puffing); Tripeptide-1; Acetyl Tetrapeptide-3; Hexapeptide-11; Arginine/Lysine Polypeptide — each peptide targets a distinct pathway, creating a comprehensive multi-signal anti-aging effect that no single peptide could achieve alone
• Sodium DNA (PDRN) — Salmon DNA Skin Repair — Polydeoxyribonucleotide fragments from salmon DNA; supports the skin's adenosine A2A receptor signaling pathway for repair and regeneration; has high biocompatibility with human skin due to structural DNA similarities; improves skin tone, luminosity and barrier function; works synergistically with the peptide complex by supporting the cellular environment in which the peptides signal
• Double-Layer Moisture Lock — Oil + Serum Phase — Neopentyl Glycol Dicaprate forms the oil layer that separates from the water-based serum phase in the bottle; when shaken, it disperses into a lightweight emulsion that applies smoothly; once on skin, the oil phase seals the hydration delivered by the serum phase beneath, reducing TEWL (transepidermal water loss) for sustained all-day moisture; this is the mechanism behind the clinical hydration improvement — the serum doesn't just hydrate, it locks hydration in
• Alpha-Arbutin + Niacinamide + Nonapeptide-1 — Triple Brightening — alpha-arbutin inhibits tyrosinase to prevent new melanin production; niacinamide blocks melanosome transfer; Nonapeptide-1 is a peptide that also inhibits tyrosinase through a different binding mechanism; three brightening actives targeting three different points in the pigmentation pathway, working alongside the PDRN repair mechanism for a comprehensive tone-correction approach
• Squalane + Jojoba Seed Oil + Allantoin + Trehalose + Panthenol — supporting hydration and soothing layer; squalane is a lightweight, non-comedogenic lipid identical to skin's natural sebum; jojoba seed oil mimics the sebaceous lipid structure for barrier support; allantoin is one of the most effective skin-soothing compounds; trehalose is a rare disaccharide humectant that protects cells from dehydration stress; panthenol attracts moisture and supports ceramide synthesis

Shake the serum well before use to mix the oil and serum layers. After cleansing and toner, apply an appropriate amount to the face and pat gently for absorption. Use morning and evening. Fragrance-free and hypoallergenic. 30ml.

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