Medicube's PDRN Pink line is built around Sodium DNA — the topical form of PDRN (Polydeoxyribonucleotide), DNA fragments extracted from salmon that support the skin's natural repair and renewal processes.

The Pink Niacinamide Milky Toner is the lightest entry point into the line: a milky, quick-absorbing toner that layers Salmon DNA with niacinamide, four ceramides, Matrixyl peptide and the Aquaxyl moisture-binding complex. The pink color comes from cyanocobalamin (Vitamin B12) and beta-carotene — not dye. Clinically tested: 48.3% improvement in hydration after 2 weeks. Non-comedogenic. Has a light vanilla and jasmine fragrance. 150ml.

• Sodium DNA (PDRN) — Salmon DNA Skin Repair — PDRN stands for Polydeoxyribonucleotide, fragments of DNA originally extracted from salmon or trout sperm cells; salmon DNA has high biocompatibility with human skin DNA because of structural similarities between fish and human genetic material; topically it is believed to support the skin's adenosine A2A receptors, which regulate repair and regeneration processes; it helps improve overall skin tone, luminosity and barrier function; Medicube uses Sodium DNA (the stabilized salt form) for better formulation stability and skin compatibility
• Niacinamide (High Position) — Brightening + Barrier + Sebum — listed third in the formula after water and glycerin, indicating a meaningful concentration; niacinamide works at multiple levels — it inhibits the transfer of melanosomes (melanin-containing vesicles) to reduce uneven pigmentation, strengthens the barrier by stimulating ceramide and natural moisturizing factor synthesis, regulates sebum production, and minimizes pore appearance; it is the formula's primary tone-correcting and skin-smoothing active, synergizing directly with the PDRN's repair effects
• 4 Ceramides (NP, NS, EOP, AP) + Palmitoyl Pentapeptide-4 (Matrixyl) — four ceramide types replace the full spectrum of lipids that comprise the skin's barrier matrix; ceramide NP is the most abundant naturally, NS and AP are structural ceramides, EOP (Ceramide 1) anchors the lamellar structure; Palmitoyl Pentapeptide-4 is the peptide in Matrixyl, Sederma's clinically validated collagen-stimulating ingredient — it signals fibroblasts to produce more collagen, elastin and hyaluronic acid; this combination makes the toner unusually active for its format
• Aquaxyl Complex — Xylitylglucoside + Anhydroxylitol + Xylitol — Aquaxyl is a patented moisture complex from Sederma (the same company behind Matrixyl); derived from sustainably sourced xylose sugar, it works at three levels: strengthens the skin's water channels (aquaporins) to improve water circulation within the skin, reinforces the stratum corneum's natural moisture reserves, and prevents TEWL (transepidermal water loss); this is a premium humectant system rarely found in toners at this price point
• Rice Bran Oil + Rice Bran Water + Centella + Madecassoside + Beta-Carotene — the soothing and antioxidant layer; rice bran is rich in ferulic acid, gamma-oryzanol and squalene for antioxidant protection and skin brightening; centella root extract and madecassoside provide barrier repair and anti-inflammatory support; beta-carotene (provitamin A) is an additional pink-hue pigment that also functions as a free-radical-scavenging antioxidant; trehalose and panthenol round out the hydration and recovery support

After cleansing, apply an appropriate amount across the entire face and tap gently to enhance absorption. Use morning and evening as the toner step in your routine. Pair with the Medicube PDRN Pink Peptide Serum as the next step for an amplified PDRN routine. 150ml.

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