Parnell's Cicamanu 92 Serum decoded: Cica (Centella Asiatica) + Manu (Manuka honey) — an overnight calming serum built for acne-prone and sensitive skin that needs barrier repair alongside inflammation control. What makes this formula stand out is melatonin — typically known as a sleep hormone, but as a topical ingredient it is one of the most potent antioxidants available, neutralizing free radicals and supporting overnight cellular repair more effectively than vitamin C in comparative studies. Lightweight gel texture, fragrance-free, absorbs without residue. 30ml.

• Melatonin — Topical Antioxidant for Overnight Repair — melatonin is produced naturally by the body during sleep and is now recognized as a powerful topical antioxidant; studies show it scavenges free radicals more effectively than vitamins C and E and helps protect skin cells from UV-induced oxidative damage even after sun exposure; applied at night it works in sync with the skin's own overnight repair cycle — supporting cellular renewal, reducing inflammation and calming redness while you sleep; an unusual and premium active rarely found in serums at this price point
• Centella Asiatica + Madecassoside — Full-Spectrum Cica — centella asiatica extract provides the full complex of cica actives including asiaticoside, asiatic acid and madecassic acid; madecassoside is additionally included as an isolated active, delivering a concentrated dose of the centella compound most associated with barrier repair, wound healing and collagen support; the dual delivery (whole extract + isolated active) is more effective than either alone for repairing a compromised barrier
• Manuka Honey (Leptospermum Scoparium) — Antibacterial + Deep Hydration — Leptospermum Scoparium is the botanical INCI for manuka honey extract; manuka from New Zealand contains methylglyoxal (MGO), a compound with exceptional antibacterial properties against the bacteria associated with acne (P. acnes); simultaneously it is one of the most effective natural humectants, drawing moisture deep into the skin; the combination of antibacterial action + deep hydration is precisely what acne-prone dehydrated skin needs
• Mugwort (Artemisia Vulgaris) + Neem (Melia Azadirachta) + Coptis Japonica (Goldenseal) — triple antibacterial and anti-inflammatory botanical complex; mugwort oil is a classic Korean calming herb that reduces redness and soothes reactive skin; neem leaf and flower are Ayurvedic antibacterials effective against acne-causing bacteria; Coptis japonica contains berberine, one of the most potent natural antibacterial and anti-inflammatory compounds — together these three address both the microbial and inflammatory causes of acne simultaneously
• Ceramide NP + Phytosphingosine + Lactobacillus Ferment — barrier rebuilding complex; ceramide NP is a primary lipid of the skin barrier; phytosphingosine is a sphingolipid precursor that supports ceramide synthesis; Lactobacillus ferment delivers probiotic-derived compounds that calm skin microbiome imbalance — a key driver of acne-prone skin sensitivity; this combination rebuilds the barrier from within rather than just sealing the surface

Apply 2–3 drops to face and pat gently to absorb. Best used as the last serum step at night before moisturizer, to work with the skin's overnight repair cycle. Can also be used in the morning. Fragrance-free. 30ml.

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